Boosting active levels of gamma-Aminobutyric acid (GABA), a neurotransmitter which has a calming effect on the brain, can help, as can interacting with the 5-HT1A receptor in the serotonin system (once activated, this receptor can aide in reducing anxiety). Antidepressants are prescribed to humans to treat anxiety, but are somewhat unpopular because they are very slow to take effect.
In contrast, CBD can trigger an anxiety-reducing effect at the 5-HT1A receptor (which is a type of serotonin (which is known as “the happy chemical”) receptor in the nervous system whose activation is linked to reducing depression and anxiety), and works to increase the prominence of GABA which is the chief inhibitory neurotransmitter in the central nervous system by acting as a positive allosteric modulator at GABA-A receptors to increase serotonin levels which in turn reduces anxiety. Basically high GABA levels leads to less anxiety and CBD helps to make these receptors more inclined to bind with GABA neurotransmitters, helping to strike a chemical balance in the brain between excitation (caused by glutamate) and inhibition (caused by GABA).
GABA is also a crucial neurotransmitter for cats, and felines have endocannabinoid and serotonin systems as well. Therefore, while there is an absence of research on CBD for cats with anxiety, joining the dots at least gives us an indication of why it may be beneficial.
allows them to benefit from CBD oil. This system allows the active ingredients in hemp to help relieve many symptoms. [ Learn more about the endocannabinoid system in dogs from caninejournal.com ]
CBD drops for dogs or CBD dog treats can ease several conditions your pup may suffer from either occasionally or chronically, including:
- Anxiety and stress
- Moderate to severe pain
- Chronic inflammation
- Arthritis
- Joint pain
- Seizures
- Digestion problems